News

The incidence of stroke continues to increase for adults and children living with sickle cell disease despite the Stroke Prevention Trial in Sickle Cell Anemia (STOP) establishing standards of care.

A new study reveals a new relationship between lipids and diseases impacting metabolism in children, which could serve as an early warning system for conditions like liver disease.

A new long-term study into long COVID has investigated how a certain population of white blood cells, called memory T cells, are established and develop during infection.

A double-blind randomized clinical trial shows that high-dose vitamin D3 doesn't improve metastatic colorectal cancer outcomes.

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

A Mayo Clinic study identifies the protein IL-4 as a cause of CAR-T cell therapy failure. Excess IL-4 leads to T-cell exhaustion. Researchers used CRISPR gene editing and monoclonal antibodies to counteract this issue.

Researchers developed the LASSARAB vaccine, using a deactivated rabies virus to protect against Lassa fever. In preclinical trials, it prevented severe disease and death in animals.

A systematic review and meta-analysis reveal that the frequency of secondary primary malignancies (SPMs) following CAR T-cell therapy is comparable to other standard treatments.

Girls exposed to certain EDCs may be more likely to start puberty early, according to new research. Early puberty is associated with an increased risk of psychosocial problems, obesity, diabetes, cardiovascular disease and breast cancer.

A study shows that gene therapy can improve vision in Bothnia dystrophy patients. By using a viral vector to deliver a functional RLBP1 gene, 11 of 12 participants experienced significant visual improvements with no serious side effects reported.