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Chemo Plus Immunotherapy Benefits Subset of Lung Cancer Patients

Researchers have discovered that combining immunotherapy and chemotherapy can overcome treatment resistance in a subset of lung cancer patients.
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Cord Blood Cells Used To Recreate a Functional Human Immune System in Mice

Researchers have used cells from cord blood to recreate a functioning human immune system in mice.
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AI-Powered Pipeline Developed for Personalized Cancer Vaccines

Scientists developed NeoDisc, a computational pipeline that combines molecular and genetic analyses with artificial intelligence to identify effective neoantigens for personalized cancer vaccines.
Cancer cells.
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Key Genetic Factors Identified for Predicting Survival for Black Patients with Leukemia

Researchers found that specific genetic mutations in Black patients with acute myeloid leukemia (AML) significantly affect survival outcomes. Their findings stress the importance of including ancestry-specific factors in AML risk stratification.
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CRISPR-Based Rapid Diagnostic for Gene Fusions in Leukemia

New technology that rapidly and simply detects disease-specific molecular alterations in two forms of leukemia could give many more patients access to lifesaving cancer treatments in the U.S. and in resource-limited countries.
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Mechanism Helping Brain Cancer Cells Multiply Discovered

A study reveals that chloride ion flows are essential for the proliferation of glioblastoma cells. Researchers found that blocking calcium-dependent chloride channels halted tumor cell division in laboratory settings.
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Pancreatic Cancer Combination Therapy May Improve Treatment Response

Researchers have discovered that a novel combination therapy promotes cancer cell death and tumor regression in pancreatic cancer.
Cancer cells.
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The Cause of a Common DNA Mutation Has Been Challenged

Researchers have discovered that the prevalent cytosine-to-thymine mutations in cancer are mainly due to mistakes in DNA replication rather than spontaneous reactions. The study identifies the role of the DNA-copying enzyme.
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Do People With MS Have an Increased Risk of Cancer?

A new study has found some cancers to be slightly more frequent in people with multiple sclerosis than in people without.
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Antiviral Enzymes Mutate DNA to Promoter Early Bladder Cancer Development

Researchers discovered that antiviral enzymes induce early mutations in bladder cancer, and standard chemotherapy causes additional mutations. The study highlights the role of complex DNA rearrangements in treatment resistance.
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