Latest App Notes & Case Studies

App Note / Case Study
Achieving Method Modernization with the New Liquid Chromatographic Gradient Allowances
USP monograph gradient separations can be successfully adjusted to maintain system suitability acceptance criteria on the Alliance iS HPLC System, as per the General Chapter <621> Chromatography (December 1, 2022).

App Note / Case Study
Streamline PFAS Detection Using Automated Solid-Phase Extraction and LC-MS/MS
This application note highlights how an automated solid-phase extraction (SPE) system can provide reliable, sensitive and accurate determination of PFAS in large-volume samples.

App Note / Case Study
Comprehensive Software for Untargeted PFAS Analysis Using HRAM Spectrometry
This application note presents a powerful software that provides a comprehensive turnkey solution for the untargeted analysis of PFAS using HRAM spectrometry.

App Note / Case Study
Detecting PFAS Contamination Using Combustion Ion Chromatography
This application note describes how combustion ion chromatography (CIC) can provide a precise and automated method for analyzing a wide range of PFAS and their precursors, enhancing understanding of contamination levels and associated health risks.

App Note / Case Study
Advanced PFAS Detection in Drinking Water Using High-Resolution Accurate Mass Spectrometry
This application note presents a validation of the EPA Method 537.1 using automated solid phase extraction (SPE) combined with HRAM spectrometry.

App Note / Case Study
Advanced Techniques for PFAS Analysis in Soil
This application note showcases the effectiveness of accelerated solvent extraction in isolating various PFAS compounds—including acids, sulfonates, fluorotelomer sulfonates, and sulfonamide compounds—from soil samples.

App Note / Case Study
Optimized Approaches for High-Throughput Protein Quantitation
This tech note explores the integration of automated sample preparation, robust LC-MS/MS analysis, and advanced data analysis software to achieve high-throughput and accurate label-free quantitation.

App Note / Case Study
Rapid Detection of Mutations Using ddPCR
This application note showcases a Droplet Digital PCR (ddPCR) workflow that can detect mutations commonly associated with non-small-cell lung cancer (NSCLC) in a single-well, 6-plex reaction.

App Note / Case Study
High-Throughput Analysis of PFAS in Air
This application note showcases a fast, high-throughput approach to measure 19 target PFAS compounds with precision and efficiency.

App Note / Case Study
The Benefits of Hydrogen Carrier Gas in PCB Analysis
This application note demonstrates how hydrogen carrier gas can be used in place of helium for GC-MS/MS analysis of PCBs, giving laboratories greater flexibility and ensuring sustained, cost-effective operations.
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