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Enzyme Engineered To Produce Threose Nucleic Acid, a Synthetic Genetic Material
Researchers have engineered an enzyme to produce synthetic genetic material, advancing the discovery of new therapeutics for cancer and autoimmune, metabolic and infectious diseases.

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CRISPR-Modified Cells Offer Remission for Autoimmune Patients
Three patients are in “safe, deep remission” after receiving a CRISPR-Cas9-modified cell therapy for autoimmune disease treatment, according to a new published study in Cell.

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Mapping Food-Microbe Interactions for Healthier Eating Choices
Researchers have created the first systematic map illustrating how specific food molecules interact with unique gut bacteria. This study highlights the variability in dietary responses among individuals.

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Inflammation in Depression Associated With Altered Immune Genes
A collaborative study between UK and Italian researchers investigates the biological mechanisms of major depressive disorder (MDD), focusing on the immune system's involvement. The research highlights gene expression profiles linked to inflammation.

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How Do Cells Recognize and Repair DNA Damage?
Researchers identified a new mechanism in the DNA damage response involving the long non-coding RNA NEAT1. Increased NEAT1 levels and methylation enhance the recognition of DNA damage.

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Largest-Ever Genetic Study on Epilepsy Uncovers Potential Therapeutic Paths
One of the largest and most diverse studies to date on genetic factors related to epilepsy has revealed potential new treatment targets.

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Living Microbes Found Within 2-Billion-Year-Old Rock
A study has identified living microbes in 2-billion-year-old rock from the Bushveld Igneous Complex in South Africa. This discovery, confirmed through advanced imaging techniques, could enhance understanding of early life on Earth.

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Frequent Use of Doxycycline Linked to Increased Antibiotic-Resistant Bacteria in the Gut Microbiome
Frequent use of doxycycline – a post-exposure prophylaxis for STIs – increases antibiotic resistance in the gut microbiome.

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Researchers Discover Backup Plan for Chromosome Division in Plants
Researchers studied Arabidopsis thaliana to understand how plants maintain chromosome stability when the critical molecule DDM1 is absent. They discovered that transposons trigger RNA interference to restore centromere function.

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Risk of Private Single-Cell Data Leakage Quantified
Single-cell RNA-seq datasets could lead to privacy violations through "linking attacks," where hackers can identify individuals' genetic and phenotypic information. This study highlights the need for stricter consent policies.
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