Latest Posters
Poster
Software for Automated Differential Expression Using 2D and 3D Representations of LC-MS Data Interactive Confirmation of Results
DeCyder™ MS is a novel software program for fully automated differential expression analysis based on LC-MS/MS data including detection, quantitation, sample to sample comparison and statistical data evaluation. Results can be interactively confirmed against original raw data through 2D and 3D data visualizations.
Poster
The Use of Software Visualization Tools for the Identification of PTM Patterns and Artefacts in LC-MS Experiments
By representing LC-MS data as a 2D-image as demonstrated in the novel DeCyder™ MS software, it is possible to identify phenomena, which are very difficult to recognize using conventional LC-MS data representation.
Poster
Sensitive Identification of Phosphopeptides in Brain Tissue using 2D-NanoLC-ESI-MSn
In this work, a biocompatible nano liquid chromatography (LC) system, Ettan™ MDLC, was used for separating tryptic peptides from brain tissue by cation exchange (SCX) to enrich the phosphopeptides followed by reversed-phase chromatography (RPC). The phosphopeptides were detected by neutral loss MS.
Poster
IGF1 Biomarker Assay Validation
This work demonstrates the development and validation of a novel clinical proteomics approach in which specific protein targets can be expeditiously and selectively isolated from acomplex biological fluid for MS characterization.
Poster
Addressing the Repoducibility Aspect of LC-MS Based Protein Identification
By using the detection, matching, and visualization approach ofDeCyder™ MS were retention time, precursor mass, and the topology of the intensity profile is utilized in combination with the matching of tandem mass spectra, it is possible to achieve repeat analysis with a very high reproducibility.
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