News

Researchers have made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis. Using innovative spatial proteomics the team identified the inflammatory JAK/STAT pathway as the main driver of disease.

Researchers have developed an advanced technique to analyze protein interactions within cells, revealing that cellular stress significantly alters these interactions. The study demonstrates how this understanding could inform drug development.

A critical transition in early human development is regulated by "jumping genes", a new study finds.

Researchers have uncovered the molecular mechanism behind the link between traumatic brain injury and Alzheimer's risk.

A study has unveiled the role of CDK5RAP2 in activating the γ-tubulin ring complex (γTuRC), a vital component for microtubule formation in cells. By using cryo-electron microscopy, the team demonstrated how CDK5RAP2 binds to γTuRC.

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study.

Scientists have shown light therapy delivered transcranially (through the skull) can aid tissue repair after mild traumatic brain injury (mTBI), offering new treatment options.

A study discovered how the MX protein traps HIV-1 and herpes viruses by assembling decoy structures that mimic nuclear pore complexes. This research enhances understanding of MX's antiviral properties.

Researchers have discovered that the prevalent cytosine-to-thymine mutations in cancer are mainly due to mistakes in DNA replication rather than spontaneous reactions. The study identifies the role of the DNA-copying enzyme.

Researchers have created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based models accurately replicate human brain development.