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Neurons labelled with green, yellow, light blue and dark blue fluorescent staining.
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Gene Therapy Enables Precise Magnetic Field Control of Brain Circuits

A new gene therapy technology enables the non-invasive control of specific brain circuits, holding promise for studying the brain and finding treatments for neurological conditions.
Antibodies.
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New Antibodies Could Mitigate Opioid Side Effects

Scientists developed a nanobody, NbE, that binds tightly to opioid receptors, blocking their activity. This could mitigate the severe side effects of opioids and lead to the creation of smaller, more effective molecules.
A needle poking into a vaccine vial.
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Potentially Longer-Lasting Covid Vaccine Targets Identified

Researchers identified more than 200 new vaccine target candidates from SARS-CoV-2, focusing on seven viral proteins beyond the Spike protein. These candidates could enhance immunity by triggering T cell responses.
Two orange pill bottles next to a model of a human brain and a doctor writing on a clipboard.
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Mutation Linked to Epilepsy Targeted With Novel Gene Therapy

NUS Medicine researchers are exploring a gene therapy approach for epilepsy linked to the KCNA2 mutation. The therapy uses Gapmer antisense oligonucleotides to target faulty RNA, restoring potassium flow and reducing excessive neuron activity.
A doctor holding a clipboard.
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Gene Therapy Shows Long-Term Benefit for Rare Pediatric Brain Disease

Researchers report that 94% of patients treated with the gene therapy eli-cel for cerebral adrenoleukodystrophy (CALD) have maintained neurological function six years post-treatment.
A cancer cell is attacked by immune cells.
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Graphene Oxide Platform Boosts the Cancer-Fighting Power of CAR T-Cell Therapy

A new graphene oxide platform that mimics the interactions between immune cells could stimulate CAR T cells to reproduce, making CAR T-cell therapy more effective.
Virus' on blue background
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Disparities in Hepatitis C Care for Reproductive-Aged Women

Identifying disparities in testing and treating hepatitis C among reproductive-aged women with opioid use disorder can improve health outcomes for all birthing parents and children.
A cancer cell is attacked by immune cells.
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Natural Killer T Cells Advance Immunotherapy for Solid Cancers

Natural killer T cells could be used to produce antitumor activity in solid tumors.
Green cannabis leaves.
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Synthetic Cannabis Reduces Agitation in Alzheimer’s by 30%

Researchers have illustrated that synthetic cannabis can reduce agitation in Alzheimer's patients by an average of 30%.
Various drug tablets on table
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Manufacturer Sponsorship Influences Reported Efficacy of Psychiatric Drugs

Psychiatric drugs are reported to be about 50% more effective in clinical trials funded by the drug’s manufacturer than when trials of the same drug are sponsored by other groups, new research shows.

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